Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors

BACKGROUND: Endothelial dysfunction (ED) has been suggested to be associated with myxomatous mitral valve disease (MMVD) in dogs. Tetrahydrobiopterin (BH4) is an important cofactor for production of the endothelium‐derived vasodilator nitric oxide (NO). Under conditions of oxidative stress, BH4 is o...

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Detalles Bibliográficos
Autores principales: Reimann, M.J., Häggström, J., Mortensen, A., Lykkesfeldt, J., Møller, J.E., Falk, T., Olsen, L.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895593/
https://www.ncbi.nlm.nih.gov/pubmed/25274442
http://dx.doi.org/10.1111/jvim.12425

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