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Generalized logical model based on network topology to capture the dynamical trends of cellular signaling pathways

BACKGROUND: Cellular responses to extracellular perturbations require signaling pathways to capture and transmit the signals. However, the underlying molecular mechanisms of signal transduction are not yet fully understood, thus detailed and comprehensive models may not be available for all the sign...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Chen, Haoting, Zhao, Li Na, Liu, Hui, Przytycka, Teresa M., Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895646/
https://www.ncbi.nlm.nih.gov/pubmed/26818802
http://dx.doi.org/10.1186/s12918-015-0249-9