LRP6 acts as a scaffold protein in cardiac gap junction assembly

Low-density lipoprotein receptor-related protein 6 (LRP6) is a Wnt co-receptor in the canonical Wnt/β-catenin signalling. Here, we report the scaffold function of LRP6 in gap junction formation of cardiomyocytes. Cardiac LRP6 is spatially restricted to intercalated discs and binds to gap junction pr...

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Detalles Bibliográficos
Autores principales: Li, Jun, Li, Changming, Liang, Dandan, Lv, Fei, Yuan, Tianyou, The, Erlinda, Ma, Xiue, Wu, Yahan, Zhen, Lixiao, Xie, Duanyang, Wang, Shiyi, Liu, Yuan, Huang, Jian, Shi, Jingyi, Liu, Yi, Shi, Dan, Xu, Liang, Lin, Li, Peng, Luying, Cui, Jianmin, Zhu, Weidong, Chen, Yi-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895718/
https://www.ncbi.nlm.nih.gov/pubmed/27250245
http://dx.doi.org/10.1038/ncomms11775

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