Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

Budding yeast Tsr1 is a ribosome biogenesis factor with sequence similarity to GTPases, which is essential for cytoplasmic steps in 40S subunit maturation. Here we present the crystal structure of Tsr1 at 3.6 Å. Tsr1 has a similar domain architecture to translational GTPases such as EF-Tu and the se...

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Detalles Bibliográficos
Autores principales: McCaughan, Urszula M., Jayachandran, Uma, Shchepachev, Vadim, Chen, Zhuo Angel, Rappsilber, Juri, Tollervey, David, Cook, Atlanta G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895721/
https://www.ncbi.nlm.nih.gov/pubmed/27250689
http://dx.doi.org/10.1038/ncomms11789

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