Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations

Although telomere length is genetically determined, mouse embryonic stem (ES) cells with telomeres of twice the normal size have been generated. Here, we use such ES cells with ‘hyper-long' telomeres, which also express green fluorescent protein (GFP), to generate chimaeric mice containing cell...

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Detalles Bibliográficos
Autores principales: Varela, Elisa, Muñoz-Lorente, Miguel A., Tejera, Agueda M., Ortega, Sagrario, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895768/
https://www.ncbi.nlm.nih.gov/pubmed/27252083
http://dx.doi.org/10.1038/ncomms11739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895768/
https://www.ncbi.nlm.nih.gov/pubmed/27252083
http://dx.doi.org/10.1038/ncomms11739

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