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Inference of domain-disease associations from domain-protein, protein-disease and disease-disease relationships
BACKGROUND: Protein domains can be viewed as portable units of biological function that defines the functional properties of proteins. Therefore, if a protein is associated with a disease, protein domains might also be associated and define disease endophenotypes. However, knowledge about such domai...
Autores principales: | Zhang, Wangshu, Coba, Marcelo P., Sun, Fengzhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895779/ https://www.ncbi.nlm.nih.gov/pubmed/26818594 http://dx.doi.org/10.1186/s12918-015-0247-y |
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