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Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study

BACKGROUND: Early morbidity and mortality are generally lower after endovascular aortic repair (EVAR), than after open repair but re-interventions and late complications are more common. The aim of the present study was to make a detailed description of re-interventions after EVAR-including incidenc...

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Autores principales: Roos, Håkan, Djerf, Henrik, Brisby Jeppsson, Ludvig, Fröjd, Victoria, Axelsson, Tomas, Jeppsson, Anders, Falkenberg, Mårten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895810/
https://www.ncbi.nlm.nih.gov/pubmed/27267131
http://dx.doi.org/10.1186/s12872-016-0309-0
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author Roos, Håkan
Djerf, Henrik
Brisby Jeppsson, Ludvig
Fröjd, Victoria
Axelsson, Tomas
Jeppsson, Anders
Falkenberg, Mårten
author_facet Roos, Håkan
Djerf, Henrik
Brisby Jeppsson, Ludvig
Fröjd, Victoria
Axelsson, Tomas
Jeppsson, Anders
Falkenberg, Mårten
author_sort Roos, Håkan
collection PubMed
description BACKGROUND: Early morbidity and mortality are generally lower after endovascular aortic repair (EVAR), than after open repair but re-interventions and late complications are more common. The aim of the present study was to make a detailed description of re-interventions after EVAR-including incidence, indications, procedures, and outcome-with special reference to non-access-related re-interventions. METHODS: This is a retrospective single-center cohort study of re-interventions after standard EVAR with special reference to non-access-related re-interventions. Consecutive patients (n = 405) treated with standard EVAR for non-ruptured (n = 337) or ruptured (n = 68) infrarenal aneurysms between 2005 and 2013 were analysed. Median follow-up was 29 months (range 0–108). RESULTS: Eighty-nine patients (22 %) underwent 113 re-interventions during follow-up. Twenty-seven patients (7 %) had 28 access related re-intervention, 65 patients (16 %) had 85 non-access related reinterventions. Non-access related re-interventions were more common in ruptured aneurysms than in unruptured aneurysms (22 vs. 15 %, p = 0.002). The most frequent indications were endoleak type I (n = 19), type II (n = 21), or type III (n = 5); stent graft migration (n = 9); and thrombosis (n = 14). The most frequent procedures were embolization of endoleak type II (n = 21), additional iliac stent graft (n = 19), proximal extension (n = 12), thrombolysis (n = 8), iliac limb bare-metal stenting (n = 6), and stent graft relining (n = 7). Endovascular technique was used in 83 % of re-interventions. Thirty-day mortality after non-access-related re-interventions was 15 % when initiated from symptoms (rupture or infection) and 0 % when initiated from follow-up findings (p = 0.014). Cumulative survival five years after EVAR was 72 % in patients with a re-intervention and 59 % in patients without (p = 0.21). CONCLUSIONS: Non-access-related re-intervention rates are still considerable after EVAR and more frequent after ruptured aneurysms. Endoleak embolization is the most frequent procedure, followed by additional iliac stent grafts. Outcomes after re-interventions are generally good, except when initiated by rupture or infection.
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spelling pubmed-48958102016-06-08 Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study Roos, Håkan Djerf, Henrik Brisby Jeppsson, Ludvig Fröjd, Victoria Axelsson, Tomas Jeppsson, Anders Falkenberg, Mårten BMC Cardiovasc Disord Research Article BACKGROUND: Early morbidity and mortality are generally lower after endovascular aortic repair (EVAR), than after open repair but re-interventions and late complications are more common. The aim of the present study was to make a detailed description of re-interventions after EVAR-including incidence, indications, procedures, and outcome-with special reference to non-access-related re-interventions. METHODS: This is a retrospective single-center cohort study of re-interventions after standard EVAR with special reference to non-access-related re-interventions. Consecutive patients (n = 405) treated with standard EVAR for non-ruptured (n = 337) or ruptured (n = 68) infrarenal aneurysms between 2005 and 2013 were analysed. Median follow-up was 29 months (range 0–108). RESULTS: Eighty-nine patients (22 %) underwent 113 re-interventions during follow-up. Twenty-seven patients (7 %) had 28 access related re-intervention, 65 patients (16 %) had 85 non-access related reinterventions. Non-access related re-interventions were more common in ruptured aneurysms than in unruptured aneurysms (22 vs. 15 %, p = 0.002). The most frequent indications were endoleak type I (n = 19), type II (n = 21), or type III (n = 5); stent graft migration (n = 9); and thrombosis (n = 14). The most frequent procedures were embolization of endoleak type II (n = 21), additional iliac stent graft (n = 19), proximal extension (n = 12), thrombolysis (n = 8), iliac limb bare-metal stenting (n = 6), and stent graft relining (n = 7). Endovascular technique was used in 83 % of re-interventions. Thirty-day mortality after non-access-related re-interventions was 15 % when initiated from symptoms (rupture or infection) and 0 % when initiated from follow-up findings (p = 0.014). Cumulative survival five years after EVAR was 72 % in patients with a re-intervention and 59 % in patients without (p = 0.21). CONCLUSIONS: Non-access-related re-intervention rates are still considerable after EVAR and more frequent after ruptured aneurysms. Endoleak embolization is the most frequent procedure, followed by additional iliac stent grafts. Outcomes after re-interventions are generally good, except when initiated by rupture or infection. BioMed Central 2016-06-06 /pmc/articles/PMC4895810/ /pubmed/27267131 http://dx.doi.org/10.1186/s12872-016-0309-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Roos, Håkan
Djerf, Henrik
Brisby Jeppsson, Ludvig
Fröjd, Victoria
Axelsson, Tomas
Jeppsson, Anders
Falkenberg, Mårten
Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title_full Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title_fullStr Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title_full_unstemmed Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title_short Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
title_sort re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895810/
https://www.ncbi.nlm.nih.gov/pubmed/27267131
http://dx.doi.org/10.1186/s12872-016-0309-0
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