IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo

BACKGROUND: Myeloid cells, such as macrophages and microglia, play a crucial role in neuroinflammation and have been recently identified as a novel therapeutic target, especially for chronic forms. The general aim would be to change the phenotype of myeloid cells from pro- to anti-inflammatory, favo...

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Detalles Bibliográficos
Autores principales: Casella, Giacomo, Garzetti, Livia, Gatta, Alberto T., Finardi, Annamaria, Maiorino, Chiara, Ruffini, Francesca, Martino, Gianvito, Muzio, Luca, Furlan, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895901/
https://www.ncbi.nlm.nih.gov/pubmed/27266518
http://dx.doi.org/10.1186/s12974-016-0596-5

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