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See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules
Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and opti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895913/ https://www.ncbi.nlm.nih.gov/pubmed/27230455 http://dx.doi.org/10.5213/inj.1632630.315 |
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author | Lee, Eunsoo Kim, Hyun Jung Sun, Woong |
author_facet | Lee, Eunsoo Kim, Hyun Jung Sun, Woong |
author_sort | Lee, Eunsoo |
collection | PubMed |
description | Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and optics allowed the visualization of neural network in the whole brain tissue with subcellular resolution. Here, we described an overview of various tissue-clearing techniques, with focus on the tissue-hydrogel mediated clearing methods, and discussed the main advantages and limitations of transparent tissue for clinical diagnosis. |
format | Online Article Text |
id | pubmed-4895913 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Korean Continence Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-48959132016-06-07 See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules Lee, Eunsoo Kim, Hyun Jung Sun, Woong Int Neurourol J Review Article Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and optics allowed the visualization of neural network in the whole brain tissue with subcellular resolution. Here, we described an overview of various tissue-clearing techniques, with focus on the tissue-hydrogel mediated clearing methods, and discussed the main advantages and limitations of transparent tissue for clinical diagnosis. Korean Continence Society 2016-05 2016-05-26 /pmc/articles/PMC4895913/ /pubmed/27230455 http://dx.doi.org/10.5213/inj.1632630.315 Text en Copyright © 2016 Korean Continence Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Lee, Eunsoo Kim, Hyun Jung Sun, Woong See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title | See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title_full | See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title_fullStr | See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title_full_unstemmed | See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title_short | See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules |
title_sort | see-through technology for biological tissue: 3-dimensional visualization of macromolecules |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895913/ https://www.ncbi.nlm.nih.gov/pubmed/27230455 http://dx.doi.org/10.5213/inj.1632630.315 |
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