Isolation of dengue virus serotype 4 genotype II from a patient with high viral load and a mixed Th1/Th17 inflammatory cytokine profile in South Brazil

BACKGROUND: We report the isolation and characterization of dengue virus (DENV) serotype 4 from a resident of Santa Fé, state of Paraná, South Brazil, in March 2013. This patient presented with hemorrhagic manifestations, high viral load and, interestingly, a mixed Th1/Th17 cytokine profile. CASE PR...

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Detalles Bibliográficos
Autores principales: Kuczera, Diogo, Bavia, Lorena, Mosimann, Ana Luiza Pamplona, Koishi, Andrea Cristine, Mazzarotto, Giovanny Augusto Camacho Antevere, Aoki, Mateus Nóbrega, Mansano, Ana Maria Ferrari, Tomeleri, Ediléia Inês, Costa Junior, Wilson Liuti, Miranda, Milena Menegazzo, Lo Sarzi, Maria, Pavanelli, Wander Rogério, Conchon-Costa, Ivete, Duarte dos Santos, Claudia Nunes, Bordignon, Juliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895951/
https://www.ncbi.nlm.nih.gov/pubmed/27267473
http://dx.doi.org/10.1186/s12985-016-0548-9

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