Cargando…
Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA
BACKGROUND: The cell adhesion and tumor suppressor protein E-cadherin is an important factor in the establishment and maintenance of epithelial integrity. E-cadherin is a single transmembrane protein, which consists of an intracellular domain (IC), a transmembrane domain (TD), and five extracellular...
Autores principales: | Schmidt, Thomas P., Goetz, Camilla, Huemer, Markus, Schneider, Gisbert, Wessler, Silja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895972/ https://www.ncbi.nlm.nih.gov/pubmed/27274359 http://dx.doi.org/10.1186/s13099-016-0112-6 |
Ejemplares similares
-
Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA
por: Schmidt, Thomas P., et al.
Publicado: (2016) -
Inhibitors of Helicobacter pylori Protease HtrA Found by ‘Virtual Ligand’ Screening Combat Bacterial Invasion of Epithelia
por: Löwer, Martin, et al.
Publicado: (2011) -
Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA
por: Tegtmeyer, Nicole, et al.
Publicado: (2015) -
Prediction of Extracellular Proteases of the Human Pathogen Helicobacter pylori Reveals Proteolytic Activity of the Hp1018/19 Protein HtrA
por: Löwer, Martin, et al.
Publicado: (2008) -
HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens
por: Abfalter, Carmen M., et al.
Publicado: (2016)