How inhibitory cues can both constrain and promote cell migration

Collective cell migration is a common feature in both embryogenesis and metastasis. By coupling studies of neural crest migration in vivo and in vitro with mathematical modeling, Szabó et al. (2016, J. Cell Biol., http://dx.doi.org/10.1083/jcb.201602083) demonstrate that the proteoglycan versican fo...

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Detalles Bibliográficos
Autor principal: Bronner, Marianne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896061/
https://www.ncbi.nlm.nih.gov/pubmed/27269064
http://dx.doi.org/10.1083/jcb.201605074
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author Bronner, Marianne E.
author_facet Bronner, Marianne E.
author_sort Bronner, Marianne E.
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description Collective cell migration is a common feature in both embryogenesis and metastasis. By coupling studies of neural crest migration in vivo and in vitro with mathematical modeling, Szabó et al. (2016, J. Cell Biol., http://dx.doi.org/10.1083/jcb.201602083) demonstrate that the proteoglycan versican forms a physical boundary that constrains neural crest cells to discrete streams, in turn facilitating their migration.
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spelling pubmed-48960612016-12-06 How inhibitory cues can both constrain and promote cell migration Bronner, Marianne E. J Cell Biol Commentary Collective cell migration is a common feature in both embryogenesis and metastasis. By coupling studies of neural crest migration in vivo and in vitro with mathematical modeling, Szabó et al. (2016, J. Cell Biol., http://dx.doi.org/10.1083/jcb.201602083) demonstrate that the proteoglycan versican forms a physical boundary that constrains neural crest cells to discrete streams, in turn facilitating their migration. The Rockefeller University Press 2016-06-06 /pmc/articles/PMC4896061/ /pubmed/27269064 http://dx.doi.org/10.1083/jcb.201605074 Text en © 2016 Bronner This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Bronner, Marianne E.
How inhibitory cues can both constrain and promote cell migration
title How inhibitory cues can both constrain and promote cell migration
title_full How inhibitory cues can both constrain and promote cell migration
title_fullStr How inhibitory cues can both constrain and promote cell migration
title_full_unstemmed How inhibitory cues can both constrain and promote cell migration
title_short How inhibitory cues can both constrain and promote cell migration
title_sort how inhibitory cues can both constrain and promote cell migration
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896061/
https://www.ncbi.nlm.nih.gov/pubmed/27269064
http://dx.doi.org/10.1083/jcb.201605074
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