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Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapy
The kinesin class of microtubule-associated motor proteins present attractive anti-cancer targets owing to their roles in key functions in dividing cells. Two interpolar mitotic kinesins Eg5 and HSET have opposing motor functions in mitotic spindle assembly with respect to microtubule movement, but...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896392/ https://www.ncbi.nlm.nih.gov/pubmed/26976726 http://dx.doi.org/10.4155/fmc.16.5 |