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Epigenetic Dysregulation Observed in Monosomy Blastocysts Further Compromises Developmental Potential
Epigenetic mechanisms such as DNA methylation regulate genomic imprinting and account for the distinct non-equivalence of the parental genomes in the embryo. Chromosomal aneuploidy, a major cause of infertility, distorts this highly regulated disparity by the presence or absence of chromosomes. The...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896457/ https://www.ncbi.nlm.nih.gov/pubmed/27271036 http://dx.doi.org/10.1371/journal.pone.0156980 |