Induction of innate immune signatures following polyepitope protein-glycoprotein B-TLR4&9 agonist immunization generates multifunctional CMV-specific cellular and humoral immunity

Recent studies have suggested that a successful subunit human cytomegalovirus (CMV) vaccine requires improved formulation to generate broad-based anti-viral immunity following immunization. Here we report the development of a non-live protein-based vaccine strategy for CMV based on a polyepitope pro...

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Detalles Bibliográficos
Autores principales: Dasari, Vijayendra, Smith, Corey, Schuessler, Andrea, Zhong, Jie, Khanna, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896525/
https://www.ncbi.nlm.nih.gov/pubmed/24463331
http://dx.doi.org/10.4161/hv.27675

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