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Palliation of Dysphagia in Carcinoma Esophagus

Esophageal carcinoma has a special place in gastrointestinal carcinomas because it contains two main types, namely, squamous cell carcinoma and adenocarcinoma. Carcinoma esophagus patients require some form of palliation because of locally advanced stage or distant metastasis, where it cannot be sub...

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Autores principales: Ramakrishnaiah, Vishnu Prasad Nelamangala, Malage, Somanath, Sreenath, G.S., Kotlapati, Sudhakar, Cyriac, Sunu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896534/
https://www.ncbi.nlm.nih.gov/pubmed/27279758
http://dx.doi.org/10.4137/CGast.S30303
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author Ramakrishnaiah, Vishnu Prasad Nelamangala
Malage, Somanath
Sreenath, G.S.
Kotlapati, Sudhakar
Cyriac, Sunu
author_facet Ramakrishnaiah, Vishnu Prasad Nelamangala
Malage, Somanath
Sreenath, G.S.
Kotlapati, Sudhakar
Cyriac, Sunu
author_sort Ramakrishnaiah, Vishnu Prasad Nelamangala
collection PubMed
description Esophageal carcinoma has a special place in gastrointestinal carcinomas because it contains two main types, namely, squamous cell carcinoma and adenocarcinoma. Carcinoma esophagus patients require some form of palliation because of locally advanced stage or distant metastasis, where it cannot be subjected to curable treatment with surgery and chemoradiation. Many modalities of palliation of dysphagia are available, but the procedure with least morbidity, mortality, and long-term palliation of dysphagia needs to be chosen for the patient. This study aims to discuss the recent trends in palliation of dysphagia with promising results and the most suitable therapy for palliation of dysphagia in a given patient. A total of 64 articles that were published between years 2005 and 2015 on various modes of palliation of dysphagia in carcinoma esophagus were studied, which were mainly randomized and prospective studies. Through this study, we conclude that stents are the first choice of therapy for palliation, which is safe and cost-effective, and they can be combined with either radiotherapy or chemotherapy for long-term palliation of dysphagia with good quality of life. Radiotherapy can be used as a second-line treatment modality.
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spelling pubmed-48965342016-06-08 Palliation of Dysphagia in Carcinoma Esophagus Ramakrishnaiah, Vishnu Prasad Nelamangala Malage, Somanath Sreenath, G.S. Kotlapati, Sudhakar Cyriac, Sunu Clin Med Insights Gastroenterol Review Esophageal carcinoma has a special place in gastrointestinal carcinomas because it contains two main types, namely, squamous cell carcinoma and adenocarcinoma. Carcinoma esophagus patients require some form of palliation because of locally advanced stage or distant metastasis, where it cannot be subjected to curable treatment with surgery and chemoradiation. Many modalities of palliation of dysphagia are available, but the procedure with least morbidity, mortality, and long-term palliation of dysphagia needs to be chosen for the patient. This study aims to discuss the recent trends in palliation of dysphagia with promising results and the most suitable therapy for palliation of dysphagia in a given patient. A total of 64 articles that were published between years 2005 and 2015 on various modes of palliation of dysphagia in carcinoma esophagus were studied, which were mainly randomized and prospective studies. Through this study, we conclude that stents are the first choice of therapy for palliation, which is safe and cost-effective, and they can be combined with either radiotherapy or chemotherapy for long-term palliation of dysphagia with good quality of life. Radiotherapy can be used as a second-line treatment modality. Libertas Academica 2016-06-06 /pmc/articles/PMC4896534/ /pubmed/27279758 http://dx.doi.org/10.4137/CGast.S30303 Text en © 2016 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Review
Ramakrishnaiah, Vishnu Prasad Nelamangala
Malage, Somanath
Sreenath, G.S.
Kotlapati, Sudhakar
Cyriac, Sunu
Palliation of Dysphagia in Carcinoma Esophagus
title Palliation of Dysphagia in Carcinoma Esophagus
title_full Palliation of Dysphagia in Carcinoma Esophagus
title_fullStr Palliation of Dysphagia in Carcinoma Esophagus
title_full_unstemmed Palliation of Dysphagia in Carcinoma Esophagus
title_short Palliation of Dysphagia in Carcinoma Esophagus
title_sort palliation of dysphagia in carcinoma esophagus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896534/
https://www.ncbi.nlm.nih.gov/pubmed/27279758
http://dx.doi.org/10.4137/CGast.S30303
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