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Modulation of Autophagy by Sorafenib: Effects on Treatment Response
The multikinase inhibitor sorafenib is, at present, the only drug approved for the treatment of hepatocellular carcinoma (HCC), one of the most lethal types of cancer worldwide. However, the increase in the number of sorafenib tumor resistant cells reduces efficiency. A better knowledge of the intra...
Autores principales: | Prieto-Domínguez, Nestor, Ordóñez, Raquel, Fernández, Anna, García-Palomo, Andres, Muntané, Jordi, González-Gallego, Javier, Mauriz, José L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896953/ https://www.ncbi.nlm.nih.gov/pubmed/27375485 http://dx.doi.org/10.3389/fphar.2016.00151 |
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