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Next-Generation Sequencing in the Mycology Lab

New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for seq...

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Autores principales: Zoll, Jan, Snelders, Eveline, Verweij, Paul E., Melchers, Willem J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896977/
https://www.ncbi.nlm.nih.gov/pubmed/27358660
http://dx.doi.org/10.1007/s12281-016-0253-6
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author Zoll, Jan
Snelders, Eveline
Verweij, Paul E.
Melchers, Willem J. G.
author_facet Zoll, Jan
Snelders, Eveline
Verweij, Paul E.
Melchers, Willem J. G.
author_sort Zoll, Jan
collection PubMed
description New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for sequence analysis provides a potential powerful tool in mycological diagnosis and research. In this review, we summarize the applications of next-generation sequencing techniques in mycology.
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spelling pubmed-48969772016-06-27 Next-Generation Sequencing in the Mycology Lab Zoll, Jan Snelders, Eveline Verweij, Paul E. Melchers, Willem J. G. Curr Fungal Infect Rep Clinical Mycology Lab Issues (K Lagrou, Section Editor) New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for sequence analysis provides a potential powerful tool in mycological diagnosis and research. In this review, we summarize the applications of next-generation sequencing techniques in mycology. Springer US 2016-03-16 2016 /pmc/articles/PMC4896977/ /pubmed/27358660 http://dx.doi.org/10.1007/s12281-016-0253-6 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Clinical Mycology Lab Issues (K Lagrou, Section Editor)
Zoll, Jan
Snelders, Eveline
Verweij, Paul E.
Melchers, Willem J. G.
Next-Generation Sequencing in the Mycology Lab
title Next-Generation Sequencing in the Mycology Lab
title_full Next-Generation Sequencing in the Mycology Lab
title_fullStr Next-Generation Sequencing in the Mycology Lab
title_full_unstemmed Next-Generation Sequencing in the Mycology Lab
title_short Next-Generation Sequencing in the Mycology Lab
title_sort next-generation sequencing in the mycology lab
topic Clinical Mycology Lab Issues (K Lagrou, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896977/
https://www.ncbi.nlm.nih.gov/pubmed/27358660
http://dx.doi.org/10.1007/s12281-016-0253-6
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