Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC

A new simple, rapid, selective and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous estimation of vasicine, glycyrrhizin, eugenol, and cineole in herbal cough syrup. The retention factors of vasicine, glycyrrhizin, eugenol, and cineole are 0.53,...

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Detalles Bibliográficos
Autores principales: Deore, Sharada L., Jaju, Payal S., Baviskar, Bhushan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897258/
https://www.ncbi.nlm.nih.gov/pubmed/27382629
http://dx.doi.org/10.1155/2014/976264
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author Deore, Sharada L.
Jaju, Payal S.
Baviskar, Bhushan A.
author_facet Deore, Sharada L.
Jaju, Payal S.
Baviskar, Bhushan A.
author_sort Deore, Sharada L.
collection PubMed
description A new simple, rapid, selective and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous estimation of vasicine, glycyrrhizin, eugenol, and cineole in herbal cough syrup. The retention factors of vasicine, glycyrrhizin, eugenol, and cineole are 0.53, 0.44, 0.75, and 0.77, respectively. Chromatography was performed on 60F(254) percolated TLC plate using n-hexane : ethyl acetate : glacial acetic acid (8.5 : 1.0 : 0.5 v/v/v). Methods are validated according to ICH guidelines and can be adopted for the routine analysis of vasicine, glycyrrhizin, eugenol and cineole in herbal cough syrup.
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spelling pubmed-48972582016-07-05 Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC Deore, Sharada L. Jaju, Payal S. Baviskar, Bhushan A. Int Sch Res Notices Research Article A new simple, rapid, selective and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous estimation of vasicine, glycyrrhizin, eugenol, and cineole in herbal cough syrup. The retention factors of vasicine, glycyrrhizin, eugenol, and cineole are 0.53, 0.44, 0.75, and 0.77, respectively. Chromatography was performed on 60F(254) percolated TLC plate using n-hexane : ethyl acetate : glacial acetic acid (8.5 : 1.0 : 0.5 v/v/v). Methods are validated according to ICH guidelines and can be adopted for the routine analysis of vasicine, glycyrrhizin, eugenol and cineole in herbal cough syrup. Hindawi Publishing Corporation 2014-10-28 /pmc/articles/PMC4897258/ /pubmed/27382629 http://dx.doi.org/10.1155/2014/976264 Text en Copyright © 2014 Sharada L. Deore et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Deore, Sharada L.
Jaju, Payal S.
Baviskar, Bhushan A.
Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title_full Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title_fullStr Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title_full_unstemmed Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title_short Simultaneous Estimation of Four Antitussive Components from Herbal Cough Syrup by HPTLC
title_sort simultaneous estimation of four antitussive components from herbal cough syrup by hptlc
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897258/
https://www.ncbi.nlm.nih.gov/pubmed/27382629
http://dx.doi.org/10.1155/2014/976264
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