In Vitro Intestinal Permeability Studies and Pharmacokinetic Evaluation of Famotidine Microemulsion for Oral Delivery

The absolute bioavailability of famotidine after oral administration is about 40–45% and absorbance only in the initial part of small intestine may be due to low intestinal permeability. Hence, an olive oil based microemulsion formulation with Tween-80 as surfactant and PEG-400 as cosurfactant was d...

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Detalles Bibliográficos
Autores principales: Jha, Sajal Kumar, Karki, Roopa, Puttegowda, Venkatesh Dinnekere, Harinarayana, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897392/
https://www.ncbi.nlm.nih.gov/pubmed/27379272
http://dx.doi.org/10.1155/2014/452051

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