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Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias

Introduction. A paraoesophageal hernia (PH) may be one reason for iron-deficiency anaemia (IDA) but is often overlooked as a cause. We aimed to assess the incidence and resolution of transfusion-dependent IDA in patients presenting for hiatal hernia surgery. Methods. We analysed a prospective databa...

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Autores principales: Skipworth, Richard J. E., Staerkle, Ralph F., Leibman, Steven, Smith, Garett S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897576/
https://www.ncbi.nlm.nih.gov/pubmed/27379280
http://dx.doi.org/10.1155/2014/479240
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author Skipworth, Richard J. E.
Staerkle, Ralph F.
Leibman, Steven
Smith, Garett S.
author_facet Skipworth, Richard J. E.
Staerkle, Ralph F.
Leibman, Steven
Smith, Garett S.
author_sort Skipworth, Richard J. E.
collection PubMed
description Introduction. A paraoesophageal hernia (PH) may be one reason for iron-deficiency anaemia (IDA) but is often overlooked as a cause. We aimed to assess the incidence and resolution of transfusion-dependent IDA in patients presenting for hiatal hernia surgery. Methods. We analysed a prospective database of patients undergoing laparoscopic hiatal repair in order to identify patients with severe IDA requiring red cell/iron transfusion. Results. Of 138 patients with PH managed over a 4-year period, 7 patients (5.1%; M : F 2 : 5; median age 62 yrs (range 57–82)) with IDA requiring red cell/iron transfusion were identified. Preoperatively, 3/7 patients underwent repetitive and unnecessary diagnostic endoscopic investigations prior to surgery. Only 2/7 ever demonstrated gastric mucosal erosions (Cameron ulcers). All patients were cured from anaemia postoperatively. Discussion. PH is an important differential diagnosis in patients with IDA, even those with marked anaemia and no endoscopically identifiable mucosal lesions. Early recognition can avoid unnecessary additional diagnostic endoscopies. Laparoscopic repair is associated with low morbidity and results in resolution of anaemia.
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spelling pubmed-48975762016-07-04 Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias Skipworth, Richard J. E. Staerkle, Ralph F. Leibman, Steven Smith, Garett S. Int Sch Res Notices Clinical Study Introduction. A paraoesophageal hernia (PH) may be one reason for iron-deficiency anaemia (IDA) but is often overlooked as a cause. We aimed to assess the incidence and resolution of transfusion-dependent IDA in patients presenting for hiatal hernia surgery. Methods. We analysed a prospective database of patients undergoing laparoscopic hiatal repair in order to identify patients with severe IDA requiring red cell/iron transfusion. Results. Of 138 patients with PH managed over a 4-year period, 7 patients (5.1%; M : F 2 : 5; median age 62 yrs (range 57–82)) with IDA requiring red cell/iron transfusion were identified. Preoperatively, 3/7 patients underwent repetitive and unnecessary diagnostic endoscopic investigations prior to surgery. Only 2/7 ever demonstrated gastric mucosal erosions (Cameron ulcers). All patients were cured from anaemia postoperatively. Discussion. PH is an important differential diagnosis in patients with IDA, even those with marked anaemia and no endoscopically identifiable mucosal lesions. Early recognition can avoid unnecessary additional diagnostic endoscopies. Laparoscopic repair is associated with low morbidity and results in resolution of anaemia. Hindawi Publishing Corporation 2014-07-24 /pmc/articles/PMC4897576/ /pubmed/27379280 http://dx.doi.org/10.1155/2014/479240 Text en Copyright © 2014 Richard J. E. Skipworth et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Skipworth, Richard J. E.
Staerkle, Ralph F.
Leibman, Steven
Smith, Garett S.
Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title_full Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title_fullStr Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title_full_unstemmed Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title_short Transfusion-Dependent Anaemia: An Overlooked Complication of Paraoesophageal Hernias
title_sort transfusion-dependent anaemia: an overlooked complication of paraoesophageal hernias
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897576/
https://www.ncbi.nlm.nih.gov/pubmed/27379280
http://dx.doi.org/10.1155/2014/479240
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