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Computational support for a scaffolding mechanism of centriole assembly
Centrioles are essential for forming cilia, flagella and centrosomes. Successful centriole assembly requires proteins of the SAS-6 family, which can form oligomeric ring structures with ninefold symmetry in vitro. While important progress has been made in understanding SAS-6 protein biophysics, the...
Autores principales: | Klein, Heinrich C. R., Guichard, Paul, Hamel, Virginie, Gönczy, Pierre, Schwarz, Ulrich S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897622/ https://www.ncbi.nlm.nih.gov/pubmed/27272020 http://dx.doi.org/10.1038/srep27075 |
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