Cargando…

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress

The maintenance of genome stability is an essential cellular process to prevent the development of diseases including cancer. hSSB1 (NABP2/ OBFC2A) is a critical component of the DNA damage response where it participates in the repair of double-strand DNA breaks and in base excision repair of oxidiz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paquet, Nicolas, Adams, Mark N., Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Leong, Vincent, Beard, Sam, Bolderson, Emma, Botting, Catherine H., O’Byrne, Kenneth J., Richard, Derek J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897654/ https://www.ncbi.nlm.nih.gov/pubmed/27273218 http://dx.doi.org/10.1038/srep27446

Ejemplares similares

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway
por: Paquet, Nicolas, et al.
Publicado: (2015)

A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution
por: Touma, Christine, et al.
Publicado: (2016)

A data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization
por: Touma, Christine, et al.
Publicado: (2017)

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage
por: Boucher, Didier, et al.
Publicado: (2021)

A Structural Perspective on the Regulation of Human Single-Stranded DNA Binding Protein 1 (hSSB1, OBFC2B) Function in DNA Repair
por: Lawson, Teegan, et al.
Publicado: (2019)

hSSB1 associates with and promotes stability of the BLM helicase
por: Croft, Laura V., et al.
Publicado: (2017)

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks
por: Bolderson, Emma, et al.
Publicado: (2014)

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response
por: Li, Yongjiang, et al.
Publicado: (2009)

Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2
por: Shi, Wei, et al.
Publicado: (2013)

Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes
por: Ashton, Nicholas W., et al.
Publicado: (2016)

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity
por: Richard, Derek J., et al.
Publicado: (2011)

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex
por: Richard, Derek J., et al.
Publicado: (2011)

INTS3 controls the hSSB1-mediated DNA damage response
por: Skaar, Jeffrey R., et al.
Publicado: (2009)

Human single-stranded DNA binding proteins are essential for maintaining genomic stability
por: Ashton, Nicholas W, et al.
Publicado: (2013)

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling
por: Kar, Ananya, et al.
Publicado: (2015)

SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites
por: Zhou, Liwen, et al.
Publicado: (2020)

FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response
por: Chen, Zhi-Wei, et al.
Publicado: (2014)

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
por: Suraweera, Amila, et al.
Publicado: (2021)

A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS‐CoV‐2
por: El‐Kamand, Serene, et al.
Publicado: (2021)

Nucleophosmin: from structure and function to disease development
por: Box, Joseph K., et al.
Publicado: (2016)

Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma
por: Li, Bowen, et al.
Publicado: (2023)

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function
por: Rose, Maddison, et al.
Publicado: (2021)

The Potential Prognostic Role of Oligosaccharide-Binding Fold-Containing Protein 2A (OBFC2A) in Triple-Negative Breast Cancer
por: Wu, Qianxue, et al.
Publicado: (2021)

Chemotherapeutic Compounds Targeting the DNA Double-Strand Break Repair Pathways: The Good, the Bad, and the Promising
por: Jekimovs, Christian, et al.
Publicado: (2014)

Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation
por: Paquet, Nicolas, et al.
Publicado: (2014)

Tumor Hypoxia Drives Genomic Instability
por: Tang, Ming, et al.
Publicado: (2021)

SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors
por: Pfeifer, Matthias, et al.
Publicado: (2019)

Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease
por: Maubaret, Cécilia G., et al.
Publicado: (2013)

DNA Binding Compatibility of the Streptococcus pneumoniae SsbA and SsbB Proteins
por: Salerno, Brenda, et al.
Publicado: (2011)

PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance
por: Rose, Maddison, et al.
Publicado: (2020)

The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy
por: Rose, Maddison, et al.
Publicado: (2022)

DeepMC-iNABP: Deep learning for multiclass identification and classification of nucleic acid-binding proteins
por: Cui, Feifei, et al.
Publicado: (2022)

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity
por: Burgess, Joshua T, et al.
Publicado: (2021)

DIRC3 and near NABP1 genetic polymorphisms are associated laryngeal squamous cell carcinoma patient survival
por: Shen, Zhen, et al.
Publicado: (2016)

Relationship between the TERT, TNIP1 and OBFC1 genetic polymorphisms and susceptibility to colorectal cancer in Chinese Han population
por: Li, Chuang, et al.
Publicado: (2017)

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy
por: Sobanski, Thais, et al.
Publicado: (2021)

RecA-SSB Interaction Modulates RecA Nucleoprotein Filament Formation on SSB-Wrapped DNA
por: Wu, Hung-Yi, et al.
Publicado: (2017)

Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding
por: Vidhyasagar, Venkatasubramanian, et al.
Publicado: (2018)

High-affinity RNA binding by a hyperthermophilic single-stranded DNA-binding protein
por: Morten, Michael J., et al.
Publicado: (2017)

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy
por: Kildey, Katrina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h58go38lg242od09opf2uo4ekr