Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia

Cytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leukemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the...

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Autores principales: Guo, Bo, Zhu, Hong Li, Li, Su Xia, Lu, Xue Chun, Fan, Hui, Da, Wan Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897657/
https://www.ncbi.nlm.nih.gov/pubmed/27298606
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author Guo, Bo
Zhu, Hong Li
Li, Su Xia
Lu, Xue Chun
Fan, Hui
Da, Wan Ming
author_facet Guo, Bo
Zhu, Hong Li
Li, Su Xia
Lu, Xue Chun
Fan, Hui
Da, Wan Ming
author_sort Guo, Bo
collection PubMed
description Cytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leukemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the abnormalities previously seen by R-banding but also improved comprehensive karyotype analysis with the following result 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13). Our report demonstrated that SKY is able to provide more information accurately for prediction of disease prognosis in adult ALL with comprehensive karyotype.
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spelling pubmed-48976572016-06-13 Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia Guo, Bo Zhu, Hong Li Li, Su Xia Lu, Xue Chun Fan, Hui Da, Wan Ming EXCLI J Case Report Cytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leukemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the abnormalities previously seen by R-banding but also improved comprehensive karyotype analysis with the following result 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13). Our report demonstrated that SKY is able to provide more information accurately for prediction of disease prognosis in adult ALL with comprehensive karyotype. Leibniz Research Centre for Working Environment and Human Factors 2012-03-01 /pmc/articles/PMC4897657/ /pubmed/27298606 Text en Copyright © 2012 Guo et al. http://www.excli.de/documents/assignment_of_rights.pdf This is an Open Access article distributed under the following Assignment of Rights http://www.excli.de/documents/assignment_of_rights.pdf. You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Case Report
Guo, Bo
Zhu, Hong Li
Li, Su Xia
Lu, Xue Chun
Fan, Hui
Da, Wan Ming
Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title_full Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title_fullStr Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title_full_unstemmed Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title_short Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
title_sort spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897657/
https://www.ncbi.nlm.nih.gov/pubmed/27298606
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