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Cardiac arrest triggers hippocampal neuronal death through autophagic and apoptotic pathways
The mechanism of neuronal death induced by ischemic injury remains unknown. We investigated whether autophagy and p53 signaling played a role in the apoptosis of hippocampal neurons following global cerebral ischemia-reperfusion (I/R) injury, in a rat model of 8-min asphyxial cardiac arrest (CA) and...
Autores principales: | Cui, Derong, Shang, Hanbing, Zhang, Xiaoli, Jiang, Wei, Jia, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897701/ https://www.ncbi.nlm.nih.gov/pubmed/27273382 http://dx.doi.org/10.1038/srep27642 |
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