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DNA Demethylation Rescues the Impaired Osteogenic Differentiation Ability of Human Periodontal Ligament Stem Cells in High Glucose

Diabetes mellitus, characterized by abnormally high blood glucose levels, gives rise to impaired bone remodeling. In response to high glucose (HG), the attenuated osteogenic differentiation capacity of human periodontal ligament stem cells (hPDLSCs) is associated with the loss of alveolar bone. Rece...

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Detalles Bibliográficos
Autores principales: Liu, Zhi, Chen, Tian, Sun, Wenhua, Yuan, Zongyi, Yu, Mei, Chen, Guoqing, Guo, Weihua, Xiao, Jingang, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897703/
https://www.ncbi.nlm.nih.gov/pubmed/27273319
http://dx.doi.org/10.1038/srep27447

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