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A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics
Despite considerable efforts, known genetic associations only explain a small fraction of predicted heritability. Regional associations combine information from multiple contiguous genetic variants and can improve variance explained at established association loci. However, regional associations are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897708/ https://www.ncbi.nlm.nih.gov/pubmed/27273519 http://dx.doi.org/10.1038/srep27644 |