Pichia pastoris Mut(S) strains are prone to misincorporation of O-methyl-l-homoserine at methionine residues when methanol is used as the sole carbon source

BACKGROUND: Over the last few decades the methylotrophic yeast Pichia pastoris has become a popular host for a wide range of products such as vaccines and therapeutic proteins. Several P. pastoris engineered strains and mutants have been developed to improve the performance of the expression system....

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Detalles Bibliográficos
Autores principales: Schotte, Peter, Dewerte, Isabelle, De Groeve, Manu, De Keyser, Saskia, De Brabandere, Veronique, Stanssens, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897801/
https://www.ncbi.nlm.nih.gov/pubmed/27267127
http://dx.doi.org/10.1186/s12934-016-0499-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897801/
https://www.ncbi.nlm.nih.gov/pubmed/27267127
http://dx.doi.org/10.1186/s12934-016-0499-2

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