Cargando…
Pichia pastoris Mut(S) strains are prone to misincorporation of O-methyl-l-homoserine at methionine residues when methanol is used as the sole carbon source
BACKGROUND: Over the last few decades the methylotrophic yeast Pichia pastoris has become a popular host for a wide range of products such as vaccines and therapeutic proteins. Several P. pastoris engineered strains and mutants have been developed to improve the performance of the expression system....
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897801/ https://www.ncbi.nlm.nih.gov/pubmed/27267127 http://dx.doi.org/10.1186/s12934-016-0499-2 |