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Improved neurite outgrowth on central nervous system myelin substrate by siRNA-mediated knockdown of Nogo receptor

PURPOSE: To investigate the in vitro effect of short interfering RNAs (siRNAs) against Nogo receptor (NgR) on neurite outgrowth under an inhibitory substrate of central nervous system (CNS) myelin. METHODS: Three siRNA sequences against NgR were designed and transfected into cerebellar granule cells...

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Detalles Bibliográficos
Autores principales: Ding, Sheng-Hao, Bao, Ying-Hui, Shen, Jian-Hong, Gao, Guo-Yi, Pan, Yao-Hua, Luo, Qi-Zhong, Jiang, Ji-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897850/
https://www.ncbi.nlm.nih.gov/pubmed/27033267
http://dx.doi.org/10.1016/j.cjtee.2015.09.008