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Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats
BACKGROUND: Our previous results showed that intrasynovial Rifamycin SV caused the lysis of synoviocites and freed the autoantigens which in turn stimulated the immunoregulatory rather than autoreactive T cell response in rheumatoid patients. Here, we hypothesize that disruption in vitro of peripher...
Autores principales: | Caruso, Innocenzo, Santandrea, Salvatore, Gismondo, Mariarita, Lombardi, Alessandra, Montrone, Franco, Caruso, Enzo Massimo, Sarzi Puttini, Piercarlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897890/ https://www.ncbi.nlm.nih.gov/pubmed/27268027 http://dx.doi.org/10.1186/s12967-016-0908-7 |
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