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Right heart in septic shock: prospective observational study

BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission...

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Autores principales: Singh, Ratender Kumar, Kumar, Sudeep, Nadig, Sreevatsa, Baronia, Arvind Kumar, Poddar, Banani, Azim, Afzal, Gurjar, Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897903/
https://www.ncbi.nlm.nih.gov/pubmed/27280022
http://dx.doi.org/10.1186/s40560-016-0159-y
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author Singh, Ratender Kumar
Kumar, Sudeep
Nadig, Sreevatsa
Baronia, Arvind Kumar
Poddar, Banani
Azim, Afzal
Gurjar, Mohan
author_facet Singh, Ratender Kumar
Kumar, Sudeep
Nadig, Sreevatsa
Baronia, Arvind Kumar
Poddar, Banani
Azim, Afzal
Gurjar, Mohan
author_sort Singh, Ratender Kumar
collection PubMed
description BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission were subjected to transthoracic echocardiography (TTE) as per the 2005 guidelines from the American Society of Echocardiography. RESULTS: Eighty-eight septic shock patients (M:F = 52:36) underwent TTE. Thirty-six patients survived. Significant differences in demographic and biochemical (laboratory and metabolic) parameters, severity scores, life-support therapies (vasopressors, ventilation), and length of ICU stay were observed between survivors and non-survivors. Right heart abnormalities of chamber dimension and systolic and diastolic function existed in 79, 25, and 86 % of patients, respectively. Right ventricle subcostal wall thickness (91 %), pulse Doppler myocardial performance index (73 %), and E/E′ (63 %) were the predominant abnormalities in chamber dimension, systolic function, and diastolic function of the right heart, respectively. However, the presence of these abnormalities did not signify poor survival in our study. CONCLUSIONS: Right heart dimensional and functional abnormalities exist in high proportions in septic shock. However, their predictability of poor outcomes remains questionable.
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spelling pubmed-48979032016-06-09 Right heart in septic shock: prospective observational study Singh, Ratender Kumar Kumar, Sudeep Nadig, Sreevatsa Baronia, Arvind Kumar Poddar, Banani Azim, Afzal Gurjar, Mohan J Intensive Care Research BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission were subjected to transthoracic echocardiography (TTE) as per the 2005 guidelines from the American Society of Echocardiography. RESULTS: Eighty-eight septic shock patients (M:F = 52:36) underwent TTE. Thirty-six patients survived. Significant differences in demographic and biochemical (laboratory and metabolic) parameters, severity scores, life-support therapies (vasopressors, ventilation), and length of ICU stay were observed between survivors and non-survivors. Right heart abnormalities of chamber dimension and systolic and diastolic function existed in 79, 25, and 86 % of patients, respectively. Right ventricle subcostal wall thickness (91 %), pulse Doppler myocardial performance index (73 %), and E/E′ (63 %) were the predominant abnormalities in chamber dimension, systolic function, and diastolic function of the right heart, respectively. However, the presence of these abnormalities did not signify poor survival in our study. CONCLUSIONS: Right heart dimensional and functional abnormalities exist in high proportions in septic shock. However, their predictability of poor outcomes remains questionable. BioMed Central 2016-06-07 /pmc/articles/PMC4897903/ /pubmed/27280022 http://dx.doi.org/10.1186/s40560-016-0159-y Text en © Singh et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Singh, Ratender Kumar
Kumar, Sudeep
Nadig, Sreevatsa
Baronia, Arvind Kumar
Poddar, Banani
Azim, Afzal
Gurjar, Mohan
Right heart in septic shock: prospective observational study
title Right heart in septic shock: prospective observational study
title_full Right heart in septic shock: prospective observational study
title_fullStr Right heart in septic shock: prospective observational study
title_full_unstemmed Right heart in septic shock: prospective observational study
title_short Right heart in septic shock: prospective observational study
title_sort right heart in septic shock: prospective observational study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897903/
https://www.ncbi.nlm.nih.gov/pubmed/27280022
http://dx.doi.org/10.1186/s40560-016-0159-y
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