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Right heart in septic shock: prospective observational study
BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897903/ https://www.ncbi.nlm.nih.gov/pubmed/27280022 http://dx.doi.org/10.1186/s40560-016-0159-y |
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author | Singh, Ratender Kumar Kumar, Sudeep Nadig, Sreevatsa Baronia, Arvind Kumar Poddar, Banani Azim, Afzal Gurjar, Mohan |
author_facet | Singh, Ratender Kumar Kumar, Sudeep Nadig, Sreevatsa Baronia, Arvind Kumar Poddar, Banani Azim, Afzal Gurjar, Mohan |
author_sort | Singh, Ratender Kumar |
collection | PubMed |
description | BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission were subjected to transthoracic echocardiography (TTE) as per the 2005 guidelines from the American Society of Echocardiography. RESULTS: Eighty-eight septic shock patients (M:F = 52:36) underwent TTE. Thirty-six patients survived. Significant differences in demographic and biochemical (laboratory and metabolic) parameters, severity scores, life-support therapies (vasopressors, ventilation), and length of ICU stay were observed between survivors and non-survivors. Right heart abnormalities of chamber dimension and systolic and diastolic function existed in 79, 25, and 86 % of patients, respectively. Right ventricle subcostal wall thickness (91 %), pulse Doppler myocardial performance index (73 %), and E/E′ (63 %) were the predominant abnormalities in chamber dimension, systolic function, and diastolic function of the right heart, respectively. However, the presence of these abnormalities did not signify poor survival in our study. CONCLUSIONS: Right heart dimensional and functional abnormalities exist in high proportions in septic shock. However, their predictability of poor outcomes remains questionable. |
format | Online Article Text |
id | pubmed-4897903 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-48979032016-06-09 Right heart in septic shock: prospective observational study Singh, Ratender Kumar Kumar, Sudeep Nadig, Sreevatsa Baronia, Arvind Kumar Poddar, Banani Azim, Afzal Gurjar, Mohan J Intensive Care Research BACKGROUND: The right heart often receives less attention during echocardiography. The situation is no different in septic shock. We prospectively investigated the echocardiographic indices of the right heart in septic shock adult patients. METHODS: Septic shock ICU patients within 24 h of admission were subjected to transthoracic echocardiography (TTE) as per the 2005 guidelines from the American Society of Echocardiography. RESULTS: Eighty-eight septic shock patients (M:F = 52:36) underwent TTE. Thirty-six patients survived. Significant differences in demographic and biochemical (laboratory and metabolic) parameters, severity scores, life-support therapies (vasopressors, ventilation), and length of ICU stay were observed between survivors and non-survivors. Right heart abnormalities of chamber dimension and systolic and diastolic function existed in 79, 25, and 86 % of patients, respectively. Right ventricle subcostal wall thickness (91 %), pulse Doppler myocardial performance index (73 %), and E/E′ (63 %) were the predominant abnormalities in chamber dimension, systolic function, and diastolic function of the right heart, respectively. However, the presence of these abnormalities did not signify poor survival in our study. CONCLUSIONS: Right heart dimensional and functional abnormalities exist in high proportions in septic shock. However, their predictability of poor outcomes remains questionable. BioMed Central 2016-06-07 /pmc/articles/PMC4897903/ /pubmed/27280022 http://dx.doi.org/10.1186/s40560-016-0159-y Text en © Singh et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Singh, Ratender Kumar Kumar, Sudeep Nadig, Sreevatsa Baronia, Arvind Kumar Poddar, Banani Azim, Afzal Gurjar, Mohan Right heart in septic shock: prospective observational study |
title | Right heart in septic shock: prospective observational study |
title_full | Right heart in septic shock: prospective observational study |
title_fullStr | Right heart in septic shock: prospective observational study |
title_full_unstemmed | Right heart in septic shock: prospective observational study |
title_short | Right heart in septic shock: prospective observational study |
title_sort | right heart in septic shock: prospective observational study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897903/ https://www.ncbi.nlm.nih.gov/pubmed/27280022 http://dx.doi.org/10.1186/s40560-016-0159-y |
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