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Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy
Determining the structure of the nuclear pore complex (NPC) imposes an enormous challenge due to its size, intricate composition and membrane-embedded nature. In vertebrates, about 1000 protein building blocks assemble into a 110-MDa complex that fuses the inner and outer membranes of a cell's...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898182/ https://www.ncbi.nlm.nih.gov/pubmed/26791760 http://dx.doi.org/10.1016/j.jmb.2016.01.004 |