Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 gene

Here we describe a spontaneous mutation in the Zdhhc13 (zinc finger, DHHC domain containing 13) gene (also called Hip14l), one of 24 genes encoding palmitoyl acyltransferase (PAT) enzymes in the mouse. This mutation (Zdhhc13(luc)) was identified as a nonsense base substitution, which results in a pr...

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Detalles Bibliográficos
Autores principales: Perez, Carlos J., Mecklenburg, Lars, Jaubert, Jean, Santamaria, Lucia Martinez, Iritani, Brian M., Espejo, Alexsandra, Napoli, Eleonora, Song, Gyu, del Río, Marcela, DiGiovanni, John, Giulivi, Cecilia, Bedford, Mark T., Dent, Sharon Y.R., Wood, Richard D., Kusewitt, Donna F., Guénet, Jean Louis, Conti, Claudio J., Benavides, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898190/
https://www.ncbi.nlm.nih.gov/pubmed/26288350
http://dx.doi.org/10.1038/jid.2015.314

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