Recurrence of acute myeloid leukemia in cryptorchid testis: case report

A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range...

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Detalles Bibliográficos
Autores principales: de Góes, Luccas Santos Patto, Lopes, Roberto Iglesias, Campos, Octavio Henrique Arcos, de Oliveira, Luiz Carlos Neves, Sant'Anna, Alexandre Crippa, Dall'Oglio, Marcos Francisco, Srougi, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898249/
https://www.ncbi.nlm.nih.gov/pubmed/24728256
http://dx.doi.org/10.1590/S1679-45082014RC2689
Descripción
Sumario:A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range and lactate dehydrogenase was raised. Computed tomography of the abdomen and pelvis revealed right testicular mass in contiguity with the inguinal canal to the ipsilateral retroperitoneum, associated with right hydronephrosis. Due to the risk of germ-cell tumor in undescended testicle, the patient underwent radical right orchiectomy. The pathological examination showed recurrence of acute myeloid leukemia in the testis. He was referred to oncology for adjuvant therapy. Our literature review found no similar cases described.

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