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Phenol-Soluble Modulins Contribute to Early Sepsis Dissemination Not Late Local USA300-Osteomyelitis Severity in Rabbits
INTRODUCTION: In bone and joint infections (BJIs), bacterial toxins are major virulence factors: Panton—Valentine leukocidin (PVL) expression leads to severe local damage, including bone distortion and abscesses, while α-hemolysin (Hla) production is associated with severe sepsis-related mortality....
Autores principales: | Davido, Benjamin, Saleh-Mghir, Azzam, Laurent, Frédéric, Danel, Claire, Couzon, Florence, Gatin, Laure, Vandenesch, François, Rasigade, Jean-Philippe, Crémieux, Anne-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898696/ https://www.ncbi.nlm.nih.gov/pubmed/27275944 http://dx.doi.org/10.1371/journal.pone.0157133 |
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