Cargando…

The Prognostic Impact of NK/NKT Cell Density in Periampullary Adenocarcinoma Differs by Morphological Type and Adjuvant Treatment

BACKGROUND: Natural killer (NK) cells and NK T cells (NKT) are vital parts of tumour immunosurveillance. However, their impact on prognosis and chemotherapy response in periampullary adenocarcinoma, including pancreatic cancer, has not yet been described. METHODS: Immune cell-specific expression of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lundgren, Sebastian, Warfvinge, Carl Fredrik, Elebro, Jacob, Heby, Margareta, Nodin, Björn, Krzyzanowska, Agnieszka, Bjartell, Anders, Leandersson, Karin, Eberhard, Jakob, Jirström, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898776/ https://www.ncbi.nlm.nih.gov/pubmed/27275582 http://dx.doi.org/10.1371/journal.pone.0156497

Ejemplares similares

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma
por: Elebro, Jacob, et al.
Publicado: (2016)

Prognostic and predictive significance of podocalyxin-like protein expression in pancreatic and periampullary adenocarcinoma
por: Heby, Margareta, et al.
Publicado: (2015)

Relationship between mismatch repair immunophenotype and long-term survival in patients with resected periampullary adenocarcinoma
por: Heby, Margareta, et al.
Publicado: (2018)

Clinical significance of stromal ER and PR expression in periampullary adenocarcinoma
por: Andersson, Gustav, et al.
Publicado: (2019)

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma
por: Lundgren, Sebastian, et al.
Publicado: (2020)

Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer
por: Elebro, Jacob, et al.
Publicado: (2016)

The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype
por: Lundgren, Sebastian, et al.
Publicado: (2017)

Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma
por: Elebro, Jacob, et al.
Publicado: (2014)

Mutational Landscape in Resected Periampullary Adenocarcinoma: Relationship With Morphology and Clinical Outcome
por: Lundgren, Sebastian, et al.
Publicado: (2019)

Chemotherapy, host response and molecular dynamics in periampullary cancer: the CHAMP study
por: Hau, Sofie Olsson, et al.
Publicado: (2020)

Reduced Expression of the Polymeric Immunoglobulin Receptor in Pancreatic and Periampullary Adenocarcinoma Signifies Tumour Progression and Poor Prognosis
por: Fristedt, Richard, et al.
Publicado: (2014)

Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas
por: Heby, Margareta, et al.
Publicado: (2020)

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma
por: Svensson, Maria C., et al.
Publicado: (2017)

Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification
por: Karnevi, Emelie, et al.
Publicado: (2017)

Use of a standardized diagnostic approach improves the prognostic information of histopathologic factors in pancreatic and periampullary adenocarcinoma
por: Elebro, Jacob, et al.
Publicado: (2014)

Expression of programmed cell death protein 1 (PD-1) and its ligand PD-L1 in colorectal cancer: Relationship with sidedness and prognosis
por: Berntsson, Jonna, et al.
Publicado: (2018)

Pre-diagnostic anthropometry, sex, and risk of colorectal cancer according to tumor immune cell composition
por: Berntsson, Jonna, et al.
Publicado: (2019)

Branching Copy-Number Evolution and Parallel Immune Profiles across the Regional Tumor Space of Resected Pancreatic Cancer
por: Petersson, Alexandra, et al.
Publicado: (2022)

Infiltration of [Formula: see text] T cells, IL-17 [Formula: see text] T cells and FoxP3 [Formula: see text] T cells in human breast cancer
por: Allaoui, Roni, et al.
Publicado: (2018)

Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion
por: Papadakos, Konstantinos S., et al.
Publicado: (2022)

Clinical impact of T cells, B cells and the PD-1/PD-L1 pathway in muscle invasive bladder cancer: a comparative study of transurethral resection and cystectomy specimens
por: Wahlin, Sara, et al.
Publicado: (2019)

The clinical impact of tumour‐infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study
por: Berntsson, Jonna, et al.
Publicado: (2017)

Trajectories of immune-related serum proteins and quality of life in patients with pancreatic and other periampullary cancer: the CHAMP study
por: Hau, Sofie Olsson, et al.
Publicado: (2023)

T cells, B cells, and PD-L1 expression in esophageal and gastric adenocarcinoma before and after neoadjuvant chemotherapy: relationship with histopathological response and survival
por: Christina Svensson, Maria, et al.
Publicado: (2021)

Sex and gender differences in treatment intention, quality of life and performance status in the first 100 patients with periampullary cancer enrolled in the CHAMP study
por: Olsson Hau, Sofie, et al.
Publicado: (2023)

Tumor-Associated CD68(+), CD163(+), and MARCO(+) Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma
por: Jeremiasen, Martin, et al.
Publicado: (2020)

PRR11 unveiled as a top candidate biomarker within the RBM3‐regulated transcriptome in pancreatic cancer
por: Olsson Hau, Sofie, et al.
Publicado: (2021)

Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study
por: Wangefjord, Sakarias, et al.
Publicado: (2011)

Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability
por: Brändstedt, Jenny, et al.
Publicado: (2014)

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma
por: Hedner, Charlotta, et al.
Publicado: (2016)

Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer
por: Lundgren, Sebastian, et al.
Publicado: (2016)

High Infiltration of CD68(+)/CD163(−) Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma
por: Svensson, Maria C., et al.
Publicado: (2022)

Associations of beta-catenin alterations and MSI screening status with expression of key cell cycle regulating proteins and survival from colorectal cancer
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
por: Medrek, Catharina, et al.
Publicado: (2012)

Associations of Anthropometric Factors with KRAS and BRAF Mutation Status of Primary Colorectal Cancer in Men and Women: A Cohort Study
por: Brändstedt, Jenny, et al.
Publicado: (2014)

Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study
por: Brändstedt, Jenny, et al.
Publicado: (2013)

Expression and prognostic significance of the polymeric immunoglobulin receptor in esophageal and gastric adenocarcinoma
por: Fristedt, Richard, et al.
Publicado: (2014)

Expression of podocalyxin-like protein is an independent prognostic biomarker in resected esophageal and gastric adenocarcinoma
por: Borg, David, et al.
Publicado: (2016)

Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival
por: Svensson, Maria C., et al.
Publicado: (2019)

Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer
por: Berntsson, Jonna, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nh8ef4c30p6qfipi7ncq9pie98