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Synthesis of the ABCDEF and FGHI ring system of yessotoxin and adriatoxin

Yessotoxin and adriatoxin are members of the polycyclic ether family of marine natural products. Outlined in this article is our synthetic approach to two subunits of these targets. Central to our strategy is a coupling sequence that employs an olefinic-ester cyclization reaction. As outlined, this...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Rainier, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898783/
https://www.ncbi.nlm.nih.gov/pubmed/26956788
http://dx.doi.org/10.1038/ja.2016.18