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X-ray structures and mechanism of the human serotonin transporter

The serotonin transporter (SERT) terminates serotonergic signaling through the sodium and chloride dependent reuptake of neurotransmitter into presynaptic neurons. SERT is a target for antidepressant and psychostimulant drugs, which block reuptake and prolong neurotransmitter signaling. Here we repo...

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Detalles Bibliográficos
Autores principales:	Coleman, Jonathan A., Green, Evan M., Gouaux, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898786/ https://www.ncbi.nlm.nih.gov/pubmed/27049939 http://dx.doi.org/10.1038/nature17629

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