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Health technology assessment of non-invasive interventions for weight loss and body shape in Iran
Background: The burden of obesity and diet-related chronic diseases is increasing in Iran, and prevention and treatment strategies are needed to address this problem. The aim of this study was to determine the outcome, cost, safety and cost-consequence of non-invasive weight loss interventions in Ir...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iran University of Medical Sciences
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898871/ https://www.ncbi.nlm.nih.gov/pubmed/27390717 |
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author | Nojomi, Marzieh Moradi-Lakeh, Maziar Velayati, Ashraf Naghibzadeh-Tahami, Ahmad Dadgostar, Haleh Ghorabi, Gholamhossein Moradi-Joo, Mohammad Yaghoubi, Mohsen |
author_facet | Nojomi, Marzieh Moradi-Lakeh, Maziar Velayati, Ashraf Naghibzadeh-Tahami, Ahmad Dadgostar, Haleh Ghorabi, Gholamhossein Moradi-Joo, Mohammad Yaghoubi, Mohsen |
author_sort | Nojomi, Marzieh |
collection | PubMed |
description | Background: The burden of obesity and diet-related chronic diseases is increasing in Iran, and prevention and treatment strategies are needed to address this problem. The aim of this study was to determine the outcome, cost, safety and cost-consequence of non-invasive weight loss interventions in Iran. Methods: We performed a systematic review to compare non-invasive interventions (cryolipolysis and radiofrequency/ ultrasonic cavitation) with semi-invasive (lipolysis) and invasive (liposuction). A sensitive electronic searching was done to find available interventional studies. Reduction of abdomen circumference (cm), reduction in fat layer thickness (%) and weight reduction (kg) were outcomes of efficacy. Meta-analysis with random models was used for pooling efficacy estimates among studies with the same follow-up duration. Average cost per intervention was estimated based on the capital, maintenance, staff, consumable and purchase costs. Results: Of 3,111 studies identified in our reviews, 13 studies assessed lipolysis, 10 cryolipolysis and 8 considered radiofrequency. Nine studies with the same follow-up duration in three different outcome group were included in meta-analysis. Radiofrequency showed an overall pooled estimate of 2.7 cm (95% CI; 2.3-3.1) of mean reduction in circumference of abdomen after intervention. Pooled estimate of reduction in fat layer thickness was 78% (95% CI; 73%-83%) after Lipolysis and a pooled estimate of weight loss was 3.01 kg (95% CI; 2.3-3.6) after lipousuction. The cost analysis revealed no significant differences between the costs of these interventions. Conclusion: The present study showed that non-invasive interventions appear to have better clinical efficacy, specifically in the body shape measurement, and less cost compared to invasive intervention (liposuction) |
format | Online Article Text |
id | pubmed-4898871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Iran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-48988712016-07-07 Health technology assessment of non-invasive interventions for weight loss and body shape in Iran Nojomi, Marzieh Moradi-Lakeh, Maziar Velayati, Ashraf Naghibzadeh-Tahami, Ahmad Dadgostar, Haleh Ghorabi, Gholamhossein Moradi-Joo, Mohammad Yaghoubi, Mohsen Med J Islam Repub Iran Original Article Background: The burden of obesity and diet-related chronic diseases is increasing in Iran, and prevention and treatment strategies are needed to address this problem. The aim of this study was to determine the outcome, cost, safety and cost-consequence of non-invasive weight loss interventions in Iran. Methods: We performed a systematic review to compare non-invasive interventions (cryolipolysis and radiofrequency/ ultrasonic cavitation) with semi-invasive (lipolysis) and invasive (liposuction). A sensitive electronic searching was done to find available interventional studies. Reduction of abdomen circumference (cm), reduction in fat layer thickness (%) and weight reduction (kg) were outcomes of efficacy. Meta-analysis with random models was used for pooling efficacy estimates among studies with the same follow-up duration. Average cost per intervention was estimated based on the capital, maintenance, staff, consumable and purchase costs. Results: Of 3,111 studies identified in our reviews, 13 studies assessed lipolysis, 10 cryolipolysis and 8 considered radiofrequency. Nine studies with the same follow-up duration in three different outcome group were included in meta-analysis. Radiofrequency showed an overall pooled estimate of 2.7 cm (95% CI; 2.3-3.1) of mean reduction in circumference of abdomen after intervention. Pooled estimate of reduction in fat layer thickness was 78% (95% CI; 73%-83%) after Lipolysis and a pooled estimate of weight loss was 3.01 kg (95% CI; 2.3-3.6) after lipousuction. The cost analysis revealed no significant differences between the costs of these interventions. Conclusion: The present study showed that non-invasive interventions appear to have better clinical efficacy, specifically in the body shape measurement, and less cost compared to invasive intervention (liposuction) Iran University of Medical Sciences 2016-04-03 /pmc/articles/PMC4898871/ /pubmed/27390717 Text en © 2016 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Nojomi, Marzieh Moradi-Lakeh, Maziar Velayati, Ashraf Naghibzadeh-Tahami, Ahmad Dadgostar, Haleh Ghorabi, Gholamhossein Moradi-Joo, Mohammad Yaghoubi, Mohsen Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title | Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title_full | Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title_fullStr | Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title_full_unstemmed | Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title_short | Health technology assessment of non-invasive interventions for weight loss and body shape in Iran |
title_sort | health technology assessment of non-invasive interventions for weight loss and body shape in iran |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898871/ https://www.ncbi.nlm.nih.gov/pubmed/27390717 |
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