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Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells
Flavonoids are assumed to exert beneficial effects in different types of cancers at high concentrations. Yet, their molecular mechanisms of action remain unknown. The present study aimed to examine the effect of quercetin on proliferation and apoptosis in HER2-expressing breast cancer cells. The ant...
Autores principales: | SEO, HYE-SOOK, KU, JIN MO, CHOI, HAN-SEOK, CHOI, YOUN KYUNG, WOO, JONG-KYU, KIM, MINSOO, KIM, ILHWAN, NA, CHANG HYEOK, HUR, HANSOL, JANG, BO-HYOUNG, SHIN, YONG CHEOL, KO, SEONG-GYU |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899028/ https://www.ncbi.nlm.nih.gov/pubmed/27175602 http://dx.doi.org/10.3892/or.2016.4786 |
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