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Interictal epileptiform discharges induce hippocampal-cortical coupling in temporal lobe epilepsy

Interactions between the hippocampus and cortex are critical for memory. Interictal epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but how they interact with physiological patterns of network activity is mostly undefined. We show in a rat model of temporal lob...

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Detalles Bibliográficos
Autores principales: Gelinas, Jennifer N., Khodagholy, Dion, Thesen, Thomas, Devinsky, Orrin, Buzsáki, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899094/
https://www.ncbi.nlm.nih.gov/pubmed/27111281
http://dx.doi.org/10.1038/nm.4084