Lactase non-persistence is directed by DNA variation-dependent epigenetic aging

Inability to digest lactose due to lactase non-persistence is a common trait in adult mammals, with the exception of certain human populations that exhibit lactase persistence. It is not clear how the lactase gene can be dramatically downregulated with age in most individuals, but remains active in...

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Detalles Bibliográficos
Autores principales: Labrie, Viviane, Buske, Orion J, Oh, Edward, Jeremian, Richie, Ptak, Carolyn, Gasiūnas, Giedrius, Maleckas, Almantas, Petereit, Rūta, Žvirbliene, Aida, Adamonis, Kęstutis, Kriukienė, Edita, Koncevičius, Karolis, Gordevičius, Juozas, Nair, Akhil, Zhang, Aiping, Ebrahimi, Sasha, Oh, Gabriel, Šikšnys, Virginijus, Kupčinskas, Limas, Brudno, Michael, Petronis, Arturas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899171/
https://www.ncbi.nlm.nih.gov/pubmed/27159559
http://dx.doi.org/10.1038/nsmb.3227

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