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Expansion of epigenetic alterations in EFEMP1 promoter predicts malignant formation in pancreatobiliary intraductal papillary mucinous neoplasms
PURPOSE: Although limited understanding exists for the presence of specific genetic mutations and aberrantly methylated genes in pancreatobiliary intraductal papillary mucinous neoplasms (IPMNs), the fundamental understanding of the dynamics of methylation expansion across CpG dinucleotides in speci...
Autores principales: | Yoshida, Kazuhiro, Nagasaka, Takeshi, Umeda, Yuzo, Tanaka, Takehiro, Kimura, Keisuke, Taniguchi, Fumitaka, Fuji, Tomokazu, Shigeyasu, Kunitoshi, Mori, Yoshiko, Yanai, Hiroyuki, Yagi, Takahito, Goel, Ajay, Fujiwara, Toshiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899496/ https://www.ncbi.nlm.nih.gov/pubmed/27095449 http://dx.doi.org/10.1007/s00432-016-2164-x |
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