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Inhibition of herpes simplex virus 1 gene expression and replication by RNase P-associated external guide sequences
An external guide sequence (EGS) is a RNA sequence which can interact with a target mRNA to form a tertiary structure like a pre-tRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, to degrade target mRNA. Previously, an in vitro selection procedure has been used by us...
Autores principales: | Liu, Jin, Shao, Luyao, Trang, Phong, Yang, Zhu, Reeves, Michael, Sun, Xu, Vu, Gia-Phong, Wang, Yu, Li, Hongjian, Zheng, Congyi, Lu, Sangwei, Liu, Fenyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899697/ https://www.ncbi.nlm.nih.gov/pubmed/27279482 http://dx.doi.org/10.1038/srep27068 |
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