The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Uses its C-Terminus to Regulate the A2B Adenosine Receptor

CFTR is an apical membrane anion channel that regulates fluid homeostasis in many organs including the airways, colon, pancreas and sweat glands. In cystic fibrosis, CFTR dysfunction causes significant morbidity/mortality. Whilst CFTR’s function as an ion channel has been well described, its ability...

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Detalles Bibliográficos
Autores principales: Watson, Michael J., Lee, Shernita L., Marklew, Abigail J., Gilmore, Rodney C., Gentzsch, Martina, Sassano, Maria F., Gray, Michael A., Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899698/
https://www.ncbi.nlm.nih.gov/pubmed/27278076
http://dx.doi.org/10.1038/srep27390

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