Cargando…
Promiscuity in the Enzymatic Catalysis of Phosphate and Sulfate Transfer
[Image: see text] The enzymes that facilitate phosphate and sulfate hydrolysis are among the most proficient natural catalysts known to date. Interestingly, a large number of these enzymes are promiscuous catalysts that exhibit both phosphatase and sulfatase activities in the same active site and, o...
Autores principales: | Pabis, Anna, Duarte, Fernanda, Kamerlin, Shina C. L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899807/ https://www.ncbi.nlm.nih.gov/pubmed/27187273 http://dx.doi.org/10.1021/acs.biochem.6b00297 |
Ejemplares similares
-
Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase
por: Purg, Miha, et al.
Publicado: (2016) -
Modeling catalytic promiscuity in the alkaline phosphatase superfamily
por: Duarte, Fernanda, et al.
Publicado: (2013) -
Resolving
Apparent Conflicts between Theoretical and
Experimental Models of Phosphate Monoester Hydrolysis
por: Duarte, Fernanda, et al.
Publicado: (2014) -
The
Competing Mechanisms of Phosphate Monoester Dianion
Hydrolysis
por: Duarte, Fernanda, et al.
Publicado: (2016) -
Similar
Active Sites and Mechanisms Do Not Lead to Cross-Promiscuity in Organophosphate
Hydrolysis: Implications for Biotherapeutic Engineering
por: Purg, Miha, et al.
Publicado: (2017)