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Local pamidronate influences fracture healing in a rodent femur fracture model: an experimental study

BACKGROUND: Bisphosphonates are a main component in the therapy of osteoporosis and other bone resorptive diseases. Previous studies have shown a positive effect of systemically applied bisphosphonates on fracture healing. Nevertheless high doses are related to side effects like osteonecrosis of the...

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Detalles Bibliográficos
Autores principales: Menzdorf, Leif, Weuster, Matthias, Klüter, Tim, Brüggemann, Stefan, Behrendt, Peter, Fitchen-Oestern, Stefanie, Varoga, Deike, Seekamp, Andreas, Purcz, Nicolai, Glueer, Claus C, Pufe, Thomas, Lippross, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899908/
https://www.ncbi.nlm.nih.gov/pubmed/27283180
http://dx.doi.org/10.1186/s12891-016-1113-9