Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons

BACKGROUND: Pathological Golgi fragmentation represents a constant pre-clinical feature of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) but its molecular mechanisms remain hitherto unclear. RESULTS: Here, we show that the severe Golgi fragmentation in transgenic muta...

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Detalles Bibliográficos
Autores principales: Bellouze, Sarah, Baillat, Gilbert, Buttigieg, Dorothée, de la Grange, Pierre, Rabouille, Catherine, Haase, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899909/
https://www.ncbi.nlm.nih.gov/pubmed/27277231
http://dx.doi.org/10.1186/s13024-016-0111-6

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