HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial

BACKGROUND: Although combined antiretroviral therapy (cART) has saved millions of lives, it is incapable of full immune reconstitution and virus eradication. The transactivator of transcription (Tat) protein is a key human immunodeficiency virus (HIV) virulence factor required for virus replication...

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Detalles Bibliográficos
Autores principales: Ensoli, Barbara, Nchabeleng, Maphoshane, Ensoli, Fabrizio, Tripiciano, Antonella, Bellino, Stefania, Picconi, Orietta, Sgadari, Cecilia, Longo, Olimpia, Tavoschi, Lara, Joffe, Daniel, Cafaro, Aurelio, Francavilla, Vittorio, Moretti, Sonia, Pavone Cossut, Maria Rosaria, Collacchi, Barbara, Arancio, Angela, Paniccia, Giovanni, Casabianca, Anna, Magnani, Mauro, Buttò, Stefano, Levendal, Elise, Ndimande, John Velaphi, Asia, Bennett, Pillay, Yogan, Garaci, Enrico, Monini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899930/
https://www.ncbi.nlm.nih.gov/pubmed/27277839
http://dx.doi.org/10.1186/s12977-016-0261-1

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